First results of the Digital OCT-Aberrometry project presented at ARVO 2023
The first results of the Digital OCT-Aberrometry (DOCTA) project were presented at the ARVO 2023 conference held in New Orleans, LA, USA (April 23-27, 2023). The demonstrated results included a wide dynamic range Digital Aberrometry in combination with Anterior Segment Imaging using a single Multimodal MHz Swept Source OCT system based on a customized modular design. The presented system and the technical approach can provide access to the full optical and anatomical information of patient’s eye which can potentially help clinicians and surgeons to devise customized treatment plan for patients in order to achieve better refractive and cataract surgery outcomes. DOCTA project is a joint collaboration between Wavesense Engineering, OCTlight and Medical University of Vienna. The project is funded by the Eureka’s Eurostars-3 programme.
27 th of April 2023
New Eurostars project to develop novel multi-model OCT device for improving cataract surgery outcome
Figure: A Digital OCT-Aberrometry (DOCTA) device will be developed in the project that can enable wavefront aberrometry together with the conventional OCT imaging of the human eye. Flexible & robust design will allow the sample arm to be mounted on a surgical microscope and to be used during the surgery.
Eurostars has granted public R&D funding to a joint international collaboration between Wavesense Engineering, Medical University of Vienna and OCTLIGHT. The consortium will develop a novel ophthalmic multimodal optical coherence tomography (OCT) device that can provide complete optical and anatomical information of patient’s eye to improve the diagnosis and treatment of eye diseases.
26 th of August 2022
Sponsors of the Eurostars DOCTA project
26 th of August 2022
Wavesense Engineering's Digital OCT-Aberrometry (DOCTA) project has been selected for grant funding under Eureka Eurostar-3 programme.
February 2022
New article published in Biomedical Optics Journal highlights Wavesense' novel OCT based Digital Aberrometry technology for human eye invivo.
Figure: (a) Aberrated en face PSF suffering from predominantly sphere and cylinder error. (b) En face after DLS- DAO correction. (c) Wavefront error map calculated using DLS-DAO. (d) Plot of Zernike coefficients. (e) Radically averagaed profile plots across the abberrated, DLS-DAO corrected and optically focused PSFs. Profiled width after DLS-DAO correction matches the with optically focus case, which demonstrates that calculated wavefront error is closer to the ground truth.
Image Courtesy: Medical University of Vienna
A proof of principle study is published in Biomedical Optics Express Journal that demonstrates a volumetric point spread function (PSF) scan technique, names as Optical Coherence Aberrometry (OCA), using a modified swept source OCT system at 1060 nm. This novel technique can provide depth resolved PSF of the optics of the human eye. Furthermore the application of Digital Lateral Shearing based Digital Adoptive Optics (DLS-DAO) on PSF data provides wavefront error map, from which refractive error values (i.e. sphere and cylinder) of the human eye can be calculated. Both ex vivo and in vivo results are presented.
September 2021
New article published in Biomedical Optics Journal highlights Wavesense' novel Digital Adaptive for cellular level human retinal imaging.
Figure A
Figure B
Figure A) SLO image of the retina with a FOV of 26° x 26° in which white dotted circle is centred at the fovea with a radius of 2° and red asterisk mark the location where OCT image is acquired.
Figure B) Gif showing the original enface OCT image of photoreceptor layer compared with images obtained after subaperture-DAO and DLS-DAO correction. DLS-DAO clearly shows superior performance with individual photoreceptor cells more clearly visible and resolvable.
Image courtesy: Medical University of Vienna.
Article published in Biomedical Optics Express Journal highlights a new digital adaptive optics technique called Digital Lateral Shearing based Digital Optics (DLS_DAO) that can detect and correct optical aberrations in OCT with high speed & accuracy. Implemented in a swept source OCT system at 1060 mm, it enables high resolution human retinal photoreceptor imaging near fovea in vivo without requiring any additional complex and expensive hardware.
March 2021